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Showing posts with label Sports Medicine. Show all posts
Showing posts with label Sports Medicine. Show all posts

Tuesday, February 5, 2008

USANA 2008 International Convention

We have just learned that, in addition to Dr. Myron Wentz and Denis Waitley, keynote speakers at the USANA 2008 International Convention, will include:


Robert Kiyosaki - http://www.richdad.com/


Paul Zane Pilzer - http://www.paulzanepilzer.com/


Tim Sales - http://www.mlmbrilliance.com/about-tim-sales.cfm



This is the first time in history that all of these speakers have appeared at the same venue together, and USANA made it happen!


Many people would pay hundreds of dollars to hear just ONE of these outstanding speakers. Now they have the opportunity to hear ALL of them just for the low price of a USANA Convention ticket.


Please pass this information on to all of your USANA team members, and encourage them to register for Convention NOW while the Early Bird ticket price is still in effect.

Vision

Vision


What will the next decade hold for you? Vision is the capacity to look beyond the moment into the vast potential of tomorrow. What is your vision?

We read in the bible about King Solomon, who in his timeless wisdom said, "Where there is no vision, the people perish." I'd like to paraphrase that statement, "Where there is no vision, a company fails." It's no accident that one of the phrases Dr. Wentz seems most fond of - and that I've heard hundreds of times over the years is, "Share my Vision."

Dr. Wentz has given voice to his vision: "I dream of a world free from pain and suffering. I dream of a world free from disease. The USANA family will be the healthiest family on earth". I'm certain some people may view Dr. Wentz' vision as impractical - or even impossible. I don't know...maybe Dr. Wentz even feels a bit uncomfortable being called a visionary. The truth is, a vision is little more than an empty dream until it is widely shared and accepted. Once that happens, it acquires the force necessary to move an organization in the intended direction. And look at us! Look at the direction we're headed. We will soon be a billion dollar company! I am proud to report that Dr. Wentz is surrounded by people who have adopted his vision and made it our own. USANA has empowered us to take a stand for our preferred future.

I realize building this business can be a bit scary at times. It takes some courage to do what we do. In order to be successful in building a USANA business we're forced to eliminate caution, we must step outside our comfort zone. Let me share three strategies that have helped me and may help you clarify your vision and reach beyond your fear:

1. Get to higher ground.

One of my favorite video clips is of Dr. Wentz standing on top of a mountain in Switzerland. You might have seen it; the camera pans around him and it appears he is looking out over the entire earth. Symbolically, we need to do the same thing...broaden our perspective and see ourselves in that big picture. Dream big. Don't sweat the small stuff. Occasionally I get a call that goes something like this: "I just got my order and one of my nutrimeal cans has a dent in it." Here is another favorite: "I don't think USANA is putting as much cotton in the top of the Poly C bottle as they used to."
Can I be frank? These people have failed the vision test!

2. Craft your own vision.

We can and should share Dr. Wentz' vision, but we need to personalize it. Tell your own story. I promise you, if you're passionate about it, your story will evolve over time. When I first started building my business back in 1994, I envisioned earning $100.00 a month. I was coming from a place of scarcity and low self-esteem. I knew I wanted to keep my daughter on the USANA products so I had to figure out a way to make $100.00 a month so I could afford to stay on autoship. I started telling our story and wow...the checks kept coming. My vision improved! As I began making a difference in the lives of others my own life began to change dramatically. I was able to look forward to a time that hadn't yet arrived. Before long I could see it and feel it as though it was real. And now it is.

3. Wake up and go to work.

Give your vision substance. Take action. If your vision stays in your mind...it is simply wishful thinking. Initiate conversations. Pick up the phone. Set up appointments. Tell your story. Use the USANA tools. Show the plan. You get my point. I've learned a valuable lesson by associating with some of USANA's elite athletes. Even professional athletes drag themselves to the gym. You simply have to exercise to get the energy to exercise. Building your business is exactly the same. I promise you won't sponsor 100% of the people you don't talk to! Just do it...ultimately, the power to achieve our vision lies within us.

Let me ask again: What will the next decade hold for you? Can you predict your future? Yes, you can - because you can create it.

Collette Larsen
USANA's Top Earner and 10-Star Diamond Director


Keywords:

AHA Scientific Statements, Alice Clegg, Alternative Medicine, antioxidants, body building, Business Opportunity, Calcium, California, Cancer, cardiovascular, diseases, cooking, diets, fitness, food, health, health and freedom, Jason Kilgore, Kilgore and USANA, Kilgore Defense Institute, Kilgore MMA, Martial Arts, men’s health, Mexico USANA, Minerals, mydreams.usana.com, nutrition, Healthy Brain, Cardiorespiratory fitness, nutritional, Recipes, Safety, Sierra Foothills Karate, nutrition, advice, sports, Sports Health, Sports Nutrition, Acupressure, Stress Management, USANA, Usana and Alice Clegg, Usana and Jason Kilgore, Usana and Sierra Foothills Karate, USANA HEALTH SCIENCES, USANA HEALTH SCIENCES DISTRIBUTOR, Traditional Chinese medicine, massage, herbs, botany, marine biology, aquaculture, sea, ocean, Utah, vitamins, wellness, Wellness Misphitz, women, fitness, womens health, Tim Sales, Naturopathic Medicine, integritas group, STI, Health and Freedom, Oriental Medicine, Acupuncture, DAOM, OMD, Metabolic Syndrome, Skin conditions, Journal of Family Practice, Complementary & Alternative Medicine, homeopathic remedies, B vitamins -- folic acid and B12, Alternative Healthcare Professional, Mind Body Health, Cherimoya, Massage Programs, Body Therapy Programs, Asian Holistic Health & massage, Chinese and other Asian systems of medicine, Tui Na Certificate, Tui Na Hand Techniques, CPR/First Aid, Asian Body Therapy, safeliving@usana.com, Mexico USANA, Ocean Conservancy

Ask Dr. Orloff About Intuitive Healing

Ask Dr. Orloff About Intuitive Healing

You have guidance and protection all around you, from the moment you are born to the day you die. Call it your guardian angels, your ancestors, a higher power, or simply love, you are not as alone as you may think. In "Step Four of Intuitive Healing: Ask For Inner Guidance" Judith Orloff, M.D. presents tips for how you can request inner guidance. She cautions you to have fun and not to try too hard. View more


Keywords:

AHA Scientific Statements, Alice Clegg, Alternative Medicine, antioxidants, body building, Business Opportunity, Calcium, California, Cancer, cardiovascular, diseases, cooking, diets, fitness, food, health, health and freedom, Jason Kilgore, Kilgore and USANA, Kilgore Defense Institute, Kilgore MMA, Martial Arts, men’s health, Mexico USANA, Minerals, mydreams.usana.com, nutrition, Healthy Brain, Cardiorespiratory fitness, nutritional, Recipes, Safety, Sierra Foothills Karate, nutrition, advice, sports, Sports Health, Sports Nutrition, Acupressure, Stress Management, USANA, Usana and Alice Clegg, Usana and Jason Kilgore, Usana and Sierra Foothills Karate, USANA HEALTH SCIENCES, USANA HEALTH SCIENCES DISTRIBUTOR, Traditional Chinese medicine, massage, herbs, botany, marine biology, aquaculture, sea, ocean, Utah, vitamins, wellness, Wellness Misphitz, women, fitness, womens health, Tim Sales, Naturopathic Medicine, integritas group, STI, Health and Freedom, Oriental Medicine, Acupuncture, DAOM, OMD, Metabolic Syndrome, Skin conditions, Journal of Family Practice, Complementary & Alternative Medicine, homeopathic remedies, B vitamins -- folic acid and B12, Alternative Healthcare Professional, Mind Body Health, Cherimoya, Massage Programs, Body Therapy Programs, Asian Holistic Health & massage, Chinese and other Asian systems of medicine, Tui Na Certificate, Tui Na Hand Techniques, CPR/First Aid, Asian Body Therapy, safeliving@usana.com, Mexico USANA, Ocean Conservancy

Thursday, January 24, 2008

USANA Cleared of Informal SEC Inquiry

Hello Success Team International,

If anyone you know has concerns about the drama which Barry Minkow stirred up in 2007, then the two releases below will be a good read for them to bring understanding and closure to this. Perhaps, save a copy of this email in your file in case someone has concerns around Minkow antics in the future. Keep in mind that USANA is dedicating considerable attention and resources to prosecute Minkow. If USANA's case goes as planned, he will most likely end up back in prison.

The more successful public companies become (examples: USANA #3 in Hottest Growth of Business Week, top 20 in Forbes for past three years, record sales for five years), the more likely it will be a target. However, rest assured that your Independent Distributor Council and USANA Senior Management are implementing several preventative measures so that we are much less vulnerable in the future to short selling schemes or critics.

Keep spreading the vision and charging to your dreams!
Jeremy StansfieldUSANA 8-Star Diamond Director

News ReleaseSEC Closes Informal Inquiry of USANA

SALT LAKE CITY--(BUSINESS WIRE)--Jan. 11, 2008--USANA Health Sciences Inc. (NASDAQ:USNA) announced today it has received a letter from the Salt Lake Regional Office of the Securities & Exchange Commission stating it has completed the informal inquiry regarding the company and is not recommending any enforcement action be taken.
USANA voluntarily disclosed the SEC's informal inquiry in March 2007, which the company believes was related to assertions appearing in the mass media. The company cooperated fully with the SEC during its inquiry.

"USANA greatly appreciates the diligence of the SEC in completing its informal inquiry, and we are pleased to put this matter behind us," said David A. Wentz, president of USANA Health Sciences Inc. "We have always been confident about the integrity of our company and take pride in our direct selling business model. All of us at USANA look forward to continuing to provide our tens of thousands of Associates and Preferred Customers worldwide with the finest nutritional products and an excellent home-based business opportunity."

Usana Health Sciences Vindicated against Stalker
Usana Health Sciences Vindicated against Stalker- January 11, 2008

David Patch
Any researcher of the Securities and Exchange Commission website looking for information on a scheme of manipulation called the ‘short and distort’ will find themselves hard pressed to find anything of substance. Unlike the extensive warnings and enforcement hearings issued by the Commission on the ‘pump and dump’ method of stock manipulation there is no such information or enforcement track record on the equally abusive ‘short and distort’.

At the present time, there are near a dozen lawsuits littered across this country where executives of public companies have accused short sellers of using access to financial media to disseminate false and misleading information about their companies. The issuers further allege that these same parties will file false claims to the Commission in order to create a bogus SEC investigation into the issuer to distort market sentiment.
The intent of the distortion of fact is to create fear and panic and drive down the market of the public issuer creating profit to any preexisting short position held prior to the news releases.

Usana Health Sciences (USNA) is one such company under the alleged attack of a ‘short and distort’ campaign.

In March 2007 USNA was trading at a market price above $60.00/share. But that was before felon Barry Minkow came calling through his access to the Wall Street Journal.

Barry Minkow has served prison time in the 1990’s for security fraud and since obtaining his freedom has developed a research company called Fraud Discovery Institute. The primary focus on the operation is to identify and then publicly trash companies Minkow perceives of running a scam.

Like former Crazy Eddie CFO and convicted felon Sam Antar, Minkow goes out and stalks public companies and presents his unsubstantiated allegations through his site distribution. Each disseminates relentless levels of negative information on the targeted companies under the guise of more material makes the story more credible.

In the disclosure statement on Fraud Discovery Institute Minkow admits that he may hold short positions in the issuers they are stalking. The disclosure statement is buried deeply into his Privacy Policy and Disclaimer statement located elsewhere and not on the individual accusatory publications.

Like Antar, Minkow has no actual evidence to support his allegations instead dressing up public information and investigative information in a manner that looks convincing but with a flaw, it is not always accurate.
Minkow and Antar use their history as a criminal in the stock market to ultimately justify the accuracy of their findings. After all we have all heard the “takes one to know one” phrase. These two should seek out patent rights to the phrase as they use it so much in their self-advertisement of who they are and why they now do what they do.
In March 2007 Minkow and the Wall Street Journal discussed his baseless allegations of fraud taking place within Usana. Minkow accused the firm of running a pyramid scheme and the WSJ ran the report in a ‘Heard on the Street’ report. The impact of the article was definitive.
Shortly after the Wall Street Journal article was released the $60.00/share market for Usana began an abrupt shift and by April 30th the market in Usana was trading below $40.00/share. By August 7 the stock had fallen to levels below $30.00/share. The market cap in Usana had dropped nearly $480 Million in a matter of 4 months after the article was relased.

A look into Minkow’s site documents the level of public stalking by Minkow during this period of ‘market adjustment’.

In fact, the attention Minkow was creating brought in the standard package of support networking as the Securities and Exchange Commission initiated an informal investigation into Minkow’s allegations and the associate firm to short sellers, Milberg Weiss, initiated a Class Action lawsuit against the company within days of the report.

Why Milberg Weiss?
Milberg Weiss is presently under indictment for providing kickbacks to planted plaintiffs in class action lawsuits filed. The federal indictment contains language stating that Weiss had advanced knowledge of companies whose market was about to come under pressure and planted lead plaintiffs in the company as long investors just prior to the market collapses.

The US Attorney has not yet detailed exactly how Milberg Weiss had the foreknowledge of the upcoming market adjustment and likewise, the SEC appears disinterested in investigating insider trading and stock manipulation charges on this foreknowledge. I would certainly want to know how this takes place if market regulation was my career responsibility and I certainly would want to understand the frequency and mechanics of how such takes place.

As for the allegations against Usana Health Sciences Minkow, Weiss, and the SEC were all proven to be wrong this week.

The Securities and Exchange Commission has concluded their informal investigation into Usana Health Sciences and issued them a clean bill of health.

The negativity about Usana created by the financial media, Minkow, and Milberg Weiss were all shown to be nothing but distortions of the truth. The distortions initiated by stock fraudster Barry Minkow created nothing short of a venue for market manipulation that benefited all short sellers in the company.

Barry Minkow himself is accused by Usana of holding a short position in the company during this window of extreme financial opportunity. The short position acting as his catalyst to increase the public dissemination of more and more distorted facts.

Under SEC policy, the SEC would not confirm or deny whether an investigation exists into Minkow or his site publications of false material. Minkow has made no public disclosures on his site of a possible SEC investigation but he does not have to either. Only public companies are required to disclose such material events.

How many more stock manipulation opportunities like this exist in the capital marketplace? Opportunities where intended distortions of fact are confused by authorities with free speech rights when it comes to public issuers.

A FOIA Request into the SEC would not shed much light on this question. The SEC responded to my request by declaring that the agency fails to maintain records of how investigations are initiated and what source created such investigations. There is no way to identify patterns of abuse by interested third parties using the complaint process to create bogus investigations and manipulate markets.

That would of course be logical in a non-logic orientated agency.

What we are aware of through public information is that court transcripts of the trail against convicted felon Anthony Elgindy provide significant insight into Mr. Elgindy’s ability to generate SEC Investigations into public companies. Convicted Felon Sam Antar has likewise admitted to gaining access to several bureaus of the SEC to launch his allegations against public issuers, and former SEC Enforcement Attorney Richard Sauer admitted in a NY Times Op-Ed piece that he utilized the short seller frequently when initiating investigations. Sauer used the Op-Ed space provided by the NY Times to canonize the short seller as the unsung hero for maintaining market controls.

At the time of the Op-Ed piece Sauer had left the SEC and was employed by the short interest hedge fund that previously provided Sauer with many of his cases. No conflict of interest there and no full and transparent disclosure in the Op-ed piece published that his employer was one and the same with the investigations he conducted.

With this evidence before us it dos not take a rocket scientist to figure out that a significant flaw in SEC enforcement exists. The financial press has provided stock manipulators with access to the public and instead of investigating the validity of such access, and taking appropriate actions against those distorting the facts the SEC focuses on the issuers and in the process aiding the manipulation process. The problem is exacerbated when felons, convicted of securities fraud, become the point of credibility in this process.

So you ask, what did the SEC’s clean bill of health disclosure have on the market in Usana? The stock gapped open up 25% today providing credence to the negative impact a bogus SEC investigation can have on a public issuer.

Usana has sued Minkow for defamation based on the allegations presented on his website and public statements issued through the financial press.

Such a lawsuit, win or lose, will never provide comfort to all those investors who lost hundreds of millions in losses. With 16 Million shares issued and outstanding the $30.00 drop in market value erased $480 Million in market capitalization. Such a decline also limited the company’s access to capital, a business impact that can never be fully evaluated.

So the next time you peruse the SEC web site take that search on the ‘short and distort’ and compare the results to the ‘pump and dump’. When you see what I have seen, write to your Congressman and ask why the SEC has turned a blind eye to this method of abuse. The evidence proves it exists, why hasn’t the SEC taken the necessary steps to clean it up? Worse, the SEC has become a major player in the fraud itself.

UPDATE: Court Documents in the Usana v. Minkow case has revealed that Sam Antar is a major financier of Minkow in this stalking attack. (See Page 4 of this attachment)

For more on this issue please visit the Host site at www.investigatethesec.com Copyright 2008


KEYWORDS:
AHA Scientific Statements AHA Statements Alice Clegg Alternative Medicine antioxidants body building Business Opportunity Calcium California Cancer cardiovascular diseases cooking diets fitness food health health and freedom Jason Kilgore Kilgore and USANA Kilgore Defense Institute Kilgore MMA Martial Arts mens health Mexico USANA Minerals mydreams.usana.com nutrition nutritional Recipes Safety Sierra Foothills Karate nutrition advice sports Sports Health Sports Nutrition Statements Stress Stress Management USANA Usana and Alice Clegg Usana and Jason Kilgore Usana and Sierra Foothills Karate USANA HEALTH SCIENCES USANA HEALTH SCIENCES DISTRIBUTOR Utah vitamins wellness Wellness Misphitz women fitness womens health

Tuesday, January 8, 2008

RESET YOUR BODY - RESET YOUR FINANCES

RESET YOUR BODY - RESET YOUR FINANCES!

Hosted by 2-Star Diamond Directors, Bud and Bunny Barth

Featured Guest Speaker: Ladd McNamara, M.D.
Expert in Nutraceutical Supplementation & Anti-Aging Medicine,
Best-selling Author and International Speaker


Create Permanent Weight Loss Without the Cravings!!!
Have More Energy, Better Focus & Feel Great
Improve Your Health and the Health of Your Family
Learn how to Create a Lifetime Stream of Residual Income
You are in Business for Yourself, but not by Yourself
Low Start Up Cost, and High Income Potential in the Next Trillion Dollar Industry: The Health & Wellness Industry
Thursday, January 17, 2007 – 7:00-8:45 PM
*****NEW LOCATION!!!!!*****
Laguna Hills Community Center
25555 Alicia Parkway
Laguna Hills, California

For Information call
Nadine Lederfine - 562-972-2753 or
Kathleen Rockney - 714-968-5102
ASSOCIATES - $10 GUESTS ARE FREE

Wednesday, December 26, 2007

IT'S INCREDIBLE

AWESOME VIDEO for you to watch & send to prospectsHey Team,Watch this 3 minute video on how USANA has helped this couple who's been in for 12 years. IT'S INCREDIBLE!!!Many of you are just starting your USANA journey (myself included), but just think of what your life can be like by staying CONSISTENT with this over a long period of time... AMAZING..

You will enjoy this video (and also send it to prospects):
http://media.usana.com/videos/aso3.shtml

Happy Holidays,

Jared Crebs

Ruby Director
Growth 25 in Process!!!

Wednesday, December 12, 2007

WEEKLY WEBCAST PRESENTATIONS for the week Dec. 10th-15th

WEEKLY WEBCAST PRESENTATIONS for the week Dec. 10th-15th

US = United States Scheduled PresentationsNZ = New Zealand Scheduled PresentationsSP = Spanish Scheduled Presentations - North America (at bottom)(Anyone can join globally)
Attendance is FREE! Use this as a valuable tool to grow your USANA business fromthe comfort of your own home! Invite guests by sending them to www.successti.com and clicking on "Webcast Events" at bottom pictures or forward this by email to them.

The following meetings will broadcast internet audio directly to your computer. Please ensure that you have Windows Media Player 9 or higher installed.

(Dial connections are OK! However, we recommend you call into the conference call number for the audio portion)FIRST TIME USERS: To save time before the meeting, check your system
to make sure it is compatible with Microsoft Office Live Meeting.

For assistance, visit Live Meeting Help and Support:
http://r.office.microsoft.com/r/rlidLiveMeeting?p1=7&p2=en_US&p3=LMInfo&p4=supportSTI WEBCAST HELP PAGE FOR LOADING LIVE MEETING
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US Monday Night December 10th STI Health & Freedom Webcast Hosts: Sherry Needham & Brian Jensen

5:00 PM Pacific (CA) 6:00 PM Mountain (UT) 7:00 PM Central (TX) 8:00 PM Eastern (FL) 2:00 PM Auckland, NZ (on Tuesday) (Time Zone Converter)Click Here to Join a Few Minutes Early - Enter Your First & Last Name

Copy/paste this Meeting URL in your browser if "Click Here" link doesn't work above...
https://www.livemeeting.com/cc/usana500/join

Meeting ID: STI-HF-MON
Role: Attendee
CONFERENCE CALL NUMBER AS BACK UP FOR AUDIO PORTION +1 (218) 936-7687 ID: 283951#
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US Wednesday Night December 12th
STI Health & Freedom Webcast Host :Matt Ryan
7:00 PM Pacific (CA) 8:00 PM Mountain (UT) 9:00 PM Central (TX) 10:00 PM Eastern (FL) 4:00 PM Auckland, NZ (on Thursday) (Time Zone Converter)Click Here to Join a Few Minutes Early - Enter Your First & Last Name Copy/paste this Meeting URL in your browser if "Click Here" link doesn't work above... https://www.livemeeting.com/cc/usana500/join
Meeting ID: STI-HF-WED Role: AttendeeCONFERENCE CALL NUMBER AS BACK UP FOR AUDIO PORTION +1 (218) 936-7687 ID: 283951#

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US Saturday Morning December 15th STI Basic Training Webcast Host: Brian Douglas 8:00 AM Pacific (CA) 9:00 AM Mountain (UT) 10:00 AM Central (TX) 11:00 AM Eastern (FL) 4:00 PM London, UK 5:00 AM Auckland, NZ (on Sunday) (Time Zone Converter)Click Here to Join a Few Minutes Early - Enter Your First & Last Name Copy/paste this Meeting URL in your browser if "Click Here" link doesn't work above... https://www.livemeeting.com/cc/usana500/join Meeting ID: STI-TR-SAT Role: AttendeeCONFERENCE CALL NUMBER AS BACK UP FOR AUDIO PORTION +1 (218) 936-7687 ID: 283951#

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NZ Wednesday Night December 12th STI Health & Freedom Webcast Hosts: Chris & Helen Bolton-Jamieson
8:00 PM Auckland, NZ 11:00 PM Pacific (CA) (Tuesday) 12:00 AM Mountain (UT) 1:00 AM Central (TX) 2:00 AM Eastern (FL) 7:00 AM London, UK (Time Zone Converter)Click Here to Join a Few Minutes Early - Enter Your First & Last Name Copy/past this Meeting URL in your browser if "Click Here" link doesn't work above... https://www.livemeeting.com/cc/usana500/join
Meeting ID: STI- NZ- HF Role: Attendee
CONFERENCE CALL NUMBER AS BACK UP FOR AUDIO PORTION +1 (218) 936-7687 ID: 283951#
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SP Wednesday Night December 12th
STI SPANISH Health & Freedom Webcast Host: Armando "Shaggy" Gonzales
7:00 PM Pacific (CA) 8:00 PM Mountain (UT) 9:00 PM Central (TX) & Mexico (South, Central, Eastern observing DST time) 10:00 PM Eastern (FL) 4:00 PM Auckland, NZ (on Thursday) (Time Zone Converter)Click Here to Join a Few Minutes Early - Enter Your First & Last Name Copy/paste this Meeting URL in your browser if "Click Here" link doesn't work above... https://www.livemeeting.com/cc/usana500/join Meeting ID: R52NPM Role: Attendee
(No conference call number, audio broadcast through computer speakers only)

Haga clic aquí para participar en Live Meeting
Dirección URL de la reunión: https://www.livemeeting.com/cc/usana500/join
Id. de la reunión: R52NPM
Función: Asistente

Esta reunión se difundirá por audio a través de Internet directamente en su equipo. Asegúrese de que tiene instalado Reproductor de Windows Media 9 o superior.

USUARIOS QUE UTILIZAN EL SISTEMA POR PRIMERA VEZ: para ahorrar tiempo antes de la reunión, compruebe el sistema para asegurarse de que es compatible con Microsoft Office Live Meeting.

Esta invitación de Live Meeting es personal; no se debe reenviar.

Para obtener ayuda, visite las secciones de Ayuda y Soporte técnico de Live Meeting: http://r.office.microsoft.com/r/rlidLiveMeeting?p1=7&p2=es_ES&p3=LMInfo&p4=support-+-----+-----+-----+-----+-----+-----+-----+-----+-


Keywords:
2-dithiole-3-thione 3H-1 antioxidants Body building cardiac cells cytotoxicity Diet Fitness Health Jason Kilgore Karate Advise martial arts Mens Health Minerals nutition nutrition oxidants Self Defense Sierra Foothills Karate Sierra Foothills Karate Advise Sierra Foothills Karate Health Advise simulated ischemia-reperfusion Sports Sports Medicine Sports Nutrition u USANA Utah Vitamins Womens Health

Integritas Group USANA Meetings - Week of Dec 16th,2007

** Monday
9:00 PM EST
- Health and Freedom WebcastBring your guests here to learn about the USANA opportunity.www.integritas-group-webcast.com - for associates www.viewthewebcast.com - for prospects712-432-3000, Bridge: 1252519:00 PM EST - Live Prospecting CallsCome listen to a top leader make live prospecting calls.605-990-0400, Code:1095879#


** Tuesday
9:00 PM EST - Health and Freedom WebcastBring your guests here to learn about the USANA opportunity.www.integritas-group-webcast.com - for associates www.viewthewebcast.com - for prospects712-432-3000, Bridge: 12525110:00 PM EST - TEAM TRAINING: Simon Chan, John Goerlitz, Kim KollerEach week's training contains important updates and critical skills that are important for success.webcast: www.training.usana.comphone: 605-990-0300 384115


#** Wednesday
8:00 PM EST - Integritas Group Info Webcast - 1 hour webcast that covers the history of Integritas, system, and community information www.integritas-group-information.com 605-990-0200 635978#9:00 PM EST - Fast Start Training Webcastwww.integritas-group-faststart.com218-486-1300, Bridge: 651953

9:00 PM EST Integritas System Support Webcast 1 hour of open Q+A on the system, training, marketing, etc led by an Integritas Expert www.integritas-group-information.com 605-990-0200 635978#11:00 PM EST - Health and Freedom WebcastBring your guests here to learn about the USANA opportunity. www.integritas-group-webcast.com - for associates www.viewthewebcast.com - for prospects712-432-3000, Bridge: 125251


** Thursday
9:00 PM EST
- Health and Freedom WebcastBring your guests here to learn about the USANA opportunity.www.integritas-group-webcast.com - for associates www.viewthewebcast.com - for prospects712-432-3000, Bridge: 1252516-10pm PST- Integritas Holiday Event San Diego, CA18861 Caminito Cantilena, Unit 24 Simon Chan and Erich Lotte are hosting a holiday event which is open to everyone in the Integritas Group. Come and meet other Integritas members to celebrate the holiday season together. Contact Erich Lotte to RSVP or for directions: erich@capitalandassets.com


** Saturday
11:00 AM EST - Integritas Group Community Call www.integritas-group-webcast.com Phone: 605-990-0400, Code: 1095879#

USANA Health Sciences to Present at Wedbush Morgan's 8th Annual California Dreamin' Conference

Friday December 7, 2:14 PM EST

SALT LAKE CITY, Dec 07, 2007 (BUSINESS WIRE) -- USANA Health Sciences, Inc. (USNA) announced today that it will present at Wedbush Morgan's 8th Annual California Dreamin' Conference in Santa Monica, California. Gilbert A. Fuller, Executive Vice President and Chief Financial Officer, is scheduled to present to leading institutional investors on Tuesday, December 11, 2007, at 10:30 a.m. PT at the Fairmont Hotel.

Those interested in listening to the webcast may access it through USANA's Web site at http://www.usanahealthsciences.com/. An archived replay of the presentation will also be available approximately one hour following the live presentation at the company's Web site and will remain accessible for 90 days.

About USANA

USANA develops and manufactures high quality nutritional and personal care products that are sold directly to Associates and Preferred Customers throughout the United States, Canada, Australia, New Zealand, Hong Kong, Japan, Taiwan, South Korea, Singapore, Mexico, Malaysia, the Netherlands, and the United Kingdom. More information on USANA can be found at http://www.usanahealthsciences.com/.

SOURCE: USANA Health Sciences, Inc.CONTACT: USANA Health Sciences, Inc.
Patrique Richards, 801-954-7100 (Investor Relations) investor.relations@us.usana.com

Copyright Business Wire 2007

Monday, December 3, 2007

Integritas Training Schedule weeek of DEC 3-8th, 2007

Here's the training schedule for the week. Please double check with the calendar in your Integritas website for any changes or if you have questions.All training events and conference calls are open to the USANA Family. Feel free to invite anyone who can benefit.

** Monday 9:00 PM EST - Health and Freedom WebcastBring your guests here to learn about the USANA opportunity.http://www.integritas-group-webcast.com/ - for associates http://www.viewthewebcast.com/ - for prospects712-432-3000, 1252519:00 PM EST - Live Prospecting CallsCome listen to a top leader make live prospecting calls.605-990-0400, 1095879#9:30 PM EST - Reset Presentation with Dr. Ray Strand and Eric Linscheid 35-minute presentation followed by questions & answershttp://www.losethecravingsnow.com/218-486-1300, 651953

** Tuesday9:00 PM EST - Health and Freedom WebcastBring your guests here to learn about the USANA opportunity.http://www.integritas-group-webcast.com/ - for associates http://www.viewthewebcast.com/ - for prospects712-432-3000, 12525110:00 PM EST - TEAM TRAINING: Simon Chan, John Goerlitz, Kim KollerThis training contains important updates and critical skills that are important for success.http://www.training.usana.com/605-990-0300 384115#

** Wednesday9:00 PM EST - Fast Start Training Webcasthttp://www.integritas-group-faststart.com/218-486-1300, 6519539:00 PM EST Integritas System Support Webcast 1 hour of open Q+A on the system, training, marketing, etc led by an Integritas Experthttp://www.integritas-group-information.com/605-990-0200, 635978#11:00 PM EST - Health and Freedom WebcastBring your guests here to learn about the USANA opportunity.http://www.integritas-group-webcast.com/ - for associates http://www.viewthewebcast.com/ - for prospects712-432-3000, 125251

** Thursday9:00 PM EST - Health and Freedom WebcastBring your guests here to learn about the USANA opportunity.http://www.integritas-group-webcast.com/ - for associates http://www.viewthewebcast.com/ - for prospects712-432-3000, 12525110:00 PM EST - CHINESE TEAM TRAINING: Simon Chan, Andrew Hu, Jacey ZhangEach week's training contains important updates and critical skills that are important for success. http://www.chinesetraining.usana.com/605-772-3001, 504810#

** Saturday11:00 AM EST - Integritas Group Community Call: Silver Director Eric Linscheidhttp://www.integritas-group-webcast.com/605-990-0400, 1095879#Eric will give you tips for getting RESET customers during this holiday season, with specific phrases to use, how to setup a RESET team for the New Year, key dates to use and step-by-step programming for success.He will NOT cover the basics on getting RESET customers. This call assumes that the listener has those basic skills.

Tuesday, November 27, 2007

USANA TRAINING EVENTS

The Live Meeting Webcast issues are NOT resolved yet, so we will be ON PHONE ONLY!

1-212-990-8000 (6063#)

6:00 p.m. Mountain -- Live Leads Training for Internet Marketing Specialists and Students

7:00 p.m. Mountain - True Health with Dr. Tim Wood, Scientist & V.P. of Research & Development

7:30 p.m. Mountain - True Wealth with Dr. Fred Cooper, V.P. of Operations

Bring your GUESTS & TEAM!

Patti Roney
Ruby Director & International Trainer
Patti@DiaMindTeam.com

Saturday, November 24, 2007

Integritas Group Community Call

11:00 AM EST -
Integritas Group Community Call
www.integritas-group-webcast.com
Phone: 605-990-0400, Code: 1095879#
Integritas Group Community Call: Diamond Director Steve Swartz

Steve will talk about the 10 Communication Qualities that Tim Sales discusses in his "Brilliant Communicator" CD set. If you're using Tim's "Professional Inviter" CD scripts, yet getting nowhere with your prospects, then the way you're communicating might just be the reason. It's HOW you say what you say that brings results!
Don't miss this important training topic!

Sunday, November 18, 2007

CHECK THIS OTHER USANA BLOG OUT

SEARCHING THROUGH THE BLOG I CAME ACROSS THIS OTHER BLOG

CHECK IT OUT:

http://www.usanachoice.blogspot.com/


http://www.safeliving.usana.com/

Seven things that will make a difference in terms of you building a large group

This is the next installment in our series of seven things that
will make a difference in terms of you building a large group.
These are what top leaders do to build a massive network.
(Sometimes consciously, sometimes instinctively.) The most
successful ones use all of them.

These seven things aren't really skills. Some are habits. Some
are mindset. And some are techniques. But they all are things
that you must use effectively to build a large business.

So let's look at number seven. And this one may surprise you.

SACRIFICE

After all, that's certainly not sexy to tell a prospect. And we
recruit all the time on money, lifestyle, and luxury. And you
know what? Network Marketing offers all those things. But not to
start.

To begin, and build something big - you're going to have to
sacrifice stuff.

You and everyone you bring into the biz are already using all 24
hours of every day. Using them doing certain things. In certain
ways. In ways that most likely keep you in your comfort zone.

You know from last week's lesson that you need at least 10 to 15
hours a week to do the business. That means you'll have to
sacrifice whatever you are now doing during that time.

Now that doesn't have to be forever. But it does have to be at
the start. I'm reading the new bestseller "The Four Hour Work
Week" by Timothy Ferriss right now. A lot of fun to read, and
some great stuff in there. But it's going to be dangerous for a
lot of people because they won't use discernment and critical
thinking.

It sounds great that he takes six months off to become a Chinese
kickboxing champion or spend a year learning to tango in Buenos
Aires. But he built up a cash flow business FIRST, before he
started his life of unending adventures.

I'm the #1 bonus check in my company and I have the kind of life
Timothy talks about in the book. I have great residual income. A
large chunk of it is passive income, and I can plan my whole
schedule around my softball teams.

And the truth is, I still sacrifice. Not because I need to -
because I choose to. Because I want to build my passive income
even higher.

My sponsor sees every blockbuster movie as soon as they come
out. He has a TiVo and watches at least five or six TV shows
regularly. I miss most of those or catch them on plane rides a
couple months later. My top leaders take more spa days than me.
Do a bunch of cruises, and take more vacations than I do.

I could do those things too and would get some enjoyment from
them. But I would rather sacrifice now, to get myself in a
better position for the future.

Don't get me wrong...

I do the stuff that brings me great joy. I'll go to the midnight
preview of a "Star Wars" or "Matrix" movie. I'll do the same
thing when a new Harry Potter book comes out and stay up all
night reading it. (Which you may have figured out I did
yesterday.) I have no compunction about turning down a $50,000
speech because it conflicts with softball playoffs. When it's
something I'm am really excited about, I'll do it. But I'm able
to do that because of previous sacrifices.

I missed some days at church when I started building my
business. Now on some Sundays my tithe check equals the other
799 people combined.

I drove long hours in a broke-mobile, working with long distance
lines when I started out. Now I travel in private jets or first
class.

My mantra was, "I will do today what others will not, so later I
can do what others cannot." And you know what? It worked.

So how about you?

Are you making the sacrifices today that will bring you true
freedom tomorrow? Or are you living in the moment of instant
gratification - which will actually keep you a grinder forever?

Give this some serious thought. And evaluate yourself in all
seven of the things we discussed in the series. Once again, they
are:

1) POSTURE
2) IMAGE
3) EVENTS
4) PERSONAL DEVELOPMENT
5) CONSISTENCY
6) COMMITMENT
7) SACRIFICE

How many of these things do you use well? Remember that the top
people in the biz use all seven. Give yourself an honest
appraisal, and then you'll know where to build from there.

Have a great week!

-Randy Gage

P.S. All of the seven keys to building and maintaining a successful
organization are timeless and will be invaluable to you for years
to come. I urge you to re-read these frequently on your journey to
fulfilling your dreams. To further reinforce these seven key
imperatives, purchase Duplication Nation, the definitive guide
to exploding your downline...

http://www.DuplicationNation.com

Saturday, November 10, 2007

CoQuinone® 30




The energy that every cell needs to function is produced through a complex process in the mitochondria, an organelle within the cell often called the cellular powerhouse. Cells store energy in a molecule called adenosine-5-triphosphate or ATP. CoQ10 is an essential part of the electron transport chain used to make ATP which is synthesized and used by every cell in the body. CoQuinone 30 contains advanced levels of CoQ10. Cells with the highest energy demands, such as in the heart, contain the highest levels of CoQ10. CoQ10 has been studied for years in the U.S., Europe, and Japan for its role in producing cellular energy and re-energizing the heart and other muscles.*


Promotes a strong and healthy cardiovascular system*
Supports energy metabolism in muscles

Patent Priority Protected formula
*These statements have not been evaluated by the Food and Drug Administration.


This product is not intended to diagnose, treat, cure, or prevent any disease.


The Importance of Good Health and How to Achieve It

Probably the most important thing in live is good health. Without good health we may experience debilitating diseases and an unnecessarily short life span. It's fairly easy to achieve good health, but it involves certain changes in your life style that are sometimes difficult to do at first. The most important to remember is to begin slowly and try to make small changes at first.The most important facet of good health is adequate exercise. Exercises help us achieve good health by strengthening our cardio-vascular system, strengthening our muscle mass and reducing the affect of stress on the body.

To ensure that exercises do not appear to be chores, it is best to find exercises that you enjoy doing rather than those that you dread. For those who prefer to be outdoors, trekking, hiking, jogging or running may be the appropriate exercise to take up. On the other hand, for those who enjoy swimming, membership to a local pool may be the answer.

There are many alternative forms of exercise that you may find beneficial. Yoga is a very popular form of exercise that helps to strengthen your body, helps you lose weight, and is great as a stress reliever. Pilates is also very poplar and deals with the core strength of your abdominals. No matter what your interests are, you are sure to find an exercise that interests you.Poor eating habits are a precursor to poor health. Healthy eating is very important in achieving and maintaining good health. Those who have poor eating habits should slowly change by taking steps such as adding a small salad to your dinner, or a piece of fruit for dessert rather than ice cream.

The aim is to slowly change the eating habits by making sure that the bulk of what you consume is nutritious and full of vitamins and minerals. Moderation in what ever you do is the key to success.Staying away from over-processed foods is a great idea. Many people love the convenience of pre-packaged frozen foods that they can just pop in the microwave for a few minutes and have a "complete" meal.

A healthier approach would be to make several nutritious meals on Sunday night and freeze portions of it. This way you still maintain the convenience of fast meals but you also know what ingredients are used in the preparation. By making small changes to your life you can be eating healthier in no time.Excessive smoking or drinking is certainly detrimental to your good health.

It's okay to occasionally imbibe, a few drinks once in a while are fine, and small amounts of red wine are actually good for you, but there is no such exception for smoking. If you smoke, go talk to your doctor to discuss a smoking cessation program. Smoking endangers your health and the health of those around you. The sooner you quit smoking, the faster your body can begin to repair the years of damage.It is easy to achieve good health.

All it takes is making some changes to your diet and lifestyle. Start by taking the stairs at work instead of getting in the elevator. Or switch that favorite lunchtime meal of hamburger and fries for a wrap and a salad. Small, easy changes are the best way to start. By making these changes now you can enjoy good health well into your golden years.

Friday, November 9, 2007

BEEN THINKING ABOUT: A SHUFFLED DECK

Life is like a game of cards. We have to work with what we’re dealt.

But what happens if we make up the rules as we go along? What if we assume that there is no real order or purpose to the shuffled deck of circumstance?

Questions like these were raised in 1990, when American educator and cultural critic (1931-2003) Neil Postman made an important address to the German Informatics Society. His speech was titled “Informing Ourselves To Death.”

Postman talked about the dangers of a society where the pursuit of information is separated from a shared sense of spiritual and social order.

To illustrate his point, Postman talked about the difference between dealing from a new deck of cards as it is taken out of the box and then doing the same with one that had been shuffled 20 times. The new deck presents the cards in a predictable order. Once the deck has been shuffled several times, there is no reason to react with disbelief or surprise to whatever card turns up.
Postman’s point was that information that is not rooted in a consistent view of life becomes like a shuffled deck of cards. He explains, “In a world without spiritual or intellectual order, nothing is unbelievable; nothing is predictable, and therefore, nothing comes as a particular surprise.” Like a voice in the wilderness, Postman declares, “We no longer have a coherent conception of ourselves, and our universe, and our relation to one another and our world. We no longer know . . . where we come from, and where we are going, or why . . . . As a consequence, our defenses against information glut have broken down; our information immune system is inoperable. We don’t know how to filter it out; we don’t know how to reduce it; we don’t know [how] to use it.

We suffer from a kind of cultural AIDS.”
Knowledge Without Roots

Neil Postman’s “Informing Ourselves To Death” describes not only the dangers of our present information-based culture but of our past as well. The opening chapters of Genesis tell how our first parents “informed themselves to death” by turning their backs on the moral order of their Creator to go after a kind of knowledge that ruined their lives.

In the middle of the growing confusion, some in every generation have looked for the “spiritual or intellectual order” that Postman talked about. In pursuit of practical answers, some have turned to the wisdom of a man named Solomon.

The Wisdom of Solomon
According to the Bible, God gave the third king of Israel an unusual capacity for wisdom and knowledge (1 Kings 4:29-34).

Solomon became a collector of proverbs. His thirst for knowledge was unquenchable. He had the curiosity of a scientist when it came to plants and animals (1 Kings 4:32-34). Leaders from all over the world came to hear his wisdom for themselves (1 Kings 10:22-24).

Even in the midst of unparalleled wealth and prosperity, Solomon would later write that the wisdom God gives is worth more than gold (Proverbs 3:13-18).

The Foolishness of Solomon

Ironically, over time Solomon ignored the counsel of the God who had given him power and wisdom (Deuteronomy 17:14-20). While multiplying personal wealth and wives, he indulged himself at the expense of those he was to serve. He even built altars to pagan gods on the hills surrounding Israel (1 Kings 11:1-11).

Late in life, Solomon wrote a short book that showed the deterioration of his mind. His thoughts had become like a shuffled deck of cards. His wisdom was mixed with despair. Until he recovered a healthy fear of God, he had no consistent way of evaluating success, failure, or even the significance of life itself (Ecclesiastes 12:1-7).

The Wisdom of Jesus

Solomon’s failures can help us understand the importance of Jesus.
Jesus, like Solomon, is remembered for His wisdom. Unlike Solomon, however, everything Jesus said and did reflected a consistent view of reality.

What really makes Jesus important to us is that He didn’t just give us words of wisdom. According to the apostle Paul, Jesus became the wisdom of God for us (1 Corinthians 1:30).
What did Paul mean when he said Jesus became wisdom for us? Was it that Jesus became our example of all that is good? Was it that His story gives us the ultimate answers to where we came from, where we are going, and why?

Paul’s own answer shows that Jesus did more than give us spiritual inspiration and answers to our moral questions. He wrote that Jesus, in addition to becoming wisdom for us, also became our “righteousness and sanctification and redemption.” He did all of this, Paul said, so that our confidence could be based on what Jesus did for us, rather than on what we could do for ourselves (vv.30-31).

In a second letter, Paul further explains that, to reconcile us to God, Jesus even became sin for us. So the apostle wrote, “He [God] made Him [Jesus] who knew no sin to be sin for us, that we might become the righteousness of God in Him” (2 Corinthians 5:21).

This is how Jesus became our wisdom. He offered Himself as the practical answer to the dilemma our first parents created when they sold their soul for “the knowledge of good and evil.” At the price of His own death, Jesus bought the right to offer life beyond the grave to anyone who would trust Him.

Why would He do it for us? Because, in the ultimate sense, Jesus is like an unshuffled deck of cards. All order, design, and purpose begin and end in Him. As our Creator, Judge, and Savior, He alone can call us back to the knowledge we’ve lost when He says, “I am the way, the truth, and the life. No one comes to the Father except through Me” (John 14:6).

And so we pray, Father in heaven, forgive us for thinking of Your Son only as our example or our teacher. Help us to see Him as the root of all true answers, the Savior who pursues us, and the One who, to show Your love, became wisdom for us. –Mart De Haan

So knowing this and life being shuffled around, you should consider signing up for your own business opportunity, be self employed, grow with a family, and be part of something good.

DONT LET LIFE SLIP BY YOU

TO SIGN UP:
https://shop.usana.com/shop/jsp/onlineServices/os2Launch.jsp?sponsorId=2444993&tagLang=en&doPlacement=0

Saturday, November 3, 2007

Antioxidants and Phase 2 Enzymes in Cardiomyocytes

Antioxidants and Phase 2 Enzymes in Cardiomyocytes:

Chemical Inducibility and Chemoprotection Against Oxidant and Simulated Ischemia-Reperfusion Injury Zhuoxiao Cao*,1, Hong Zhu*, Li Zhang*, Xue Zhao, Jay L. Zweier* and Yunbo Li*,2
* Davis Heart and Lung Research Institute, Department of Internal Medicine and Division of Cardiovascular Medicine, The Ohio State University Medical Center, Columbus, Ohio 43210; and Department of Cardiology, Changzheng Hospital, The Second Military Medical University, 415 Fengyang Road, Shanghai 200003, China

The increasing recognition of the role for oxidative stress in cardiac disorders has led to extensive investigation on the protection by exogenous antioxidants against oxidative cardiac injury. On the other hand, another strategy for protecting against oxidative cardiac injury may be through upregulation of the endogenous antioxidants and phase 2 enzymes in the myocardium by chemical inducers. However, our current understanding of the chemical inducibility of cardiac cellular antioxidants and phase 2 enzymes is very limited.

In this study, using rat cardiac H9c2 cells we have characterized the concentration- and time-dependent induction of cellular antioxidants and phase 2 enzymes by 3H-1,2-dithiole-3-thione (D3T), and the resultant chemoprotective effects on oxidative cardiac cell injury. Incubation of H9c2 cells with D3T resulted in a marked concentration- and time-dependent induction of a number of cellular antioxidants and phase 2 enzymes, including catalase, reduced glutathione (GSH), GSH peroxidase, glutathione reductase (GR), GSH S-transferase (GST), and NAD(P)H:quinone oxidoreductase-1 (NQO1). D3T treatment of H9c2 cells also caused an increase in mRNA expression of catalase, -glutamylcysteine ligase catalytic subunit, GR, GSTA1, M1 and P1, and NQO1.

Moreover, both mRNA and protein expression of Nrf2 were induced in D3T-treated cells. D3T pretreatment led to a marked protection against H9c2 cell injury elicited by various oxidants and simulated ischemia-reperfusion. D3T pretreatment also resulted in decreased intracellular accumulation of reactive oxygen in H9c2 cells after exposure to the oxidants as well as simulated ischemia-reperfusion. This study demonstrates that a series of endogenous antioxidants and phase 2 enzymes in H9c2 cells can be induced by D3T in a concentration- and time-dependent fashion, and that the D3T-upregulated cellular defenses are accompanied by a markedly increased resistance to oxidative cardiac cell injury.


Key Words: cardiac cells • 3H-1,2-dithiole-3-thione • antioxidants • oxidants • simulated ischemia-reperfusion • cytotoxicity

Antioxidant Vitamin Supplements and Cardiovascular Disease

Antioxidant Vitamin Supplements and Cardiovascular Disease

Penny M. Kris-Etherton, PhD, RD; Alice H. Lichtenstein, DSc; Barbara V. Howard, PhD; Daniel Steinberg, MD, PhD; Joseph L. Witztum, MD, for the Nutrition Committee of the American Heart Association Council on Nutrition, Physical Activity, and Metabolism


Key Words: AHA Science Advisory • antioxidants • nutrition • coronary disease • cardiovascular diseases

The American Heart Association (AHA) has had a long-standing commitment to provide information about the role of nutrition in cardiovascular disease (CVD) risk reduction. Many activities have been and are currently directed toward this objective, including issuing AHA Dietary Guidelines periodically (most recently in 20001) and Science Advisories and Statements on an ongoing basis to review emerging nutrition-related issues. The objective of the AHA Dietary Guidelines is to promote healthful dietary patterns. A consistent focus since the inception of the AHA Dietary Guidelines has been to reduce saturated fat (and trans fat) and cholesterol intake, as well as to increase dietary fiber consumption. Collectively, all the AHA Dietary Guidelines have supported a dietary pattern that promotes the consumption of diets rich in fruits, vegetables, whole grains, low-fat or nonfat dairy products, fish, legumes, poultry, and lean meats. This dietary pattern has a low energy density to promote weight control and a high nutrient density to meet all nutrient needs.

As reviewed in the first AHA Science Advisory2 on antioxidant vitamins, epidemiological and population studies reported that some micronutrients may beneficially affect CVD risk (ie, antioxidant vitamins such as vitamin E, vitamin C, and ß-carotene). Recent epidemiological evidence3 is consistent with the earlier epidemiological and population studies (reviewed in the first Science Advisory).2 These findings have been supported by in vitro studies that have established a role of oxidative processes in the development of the atherosclerotic plaque. Underlying the atherosclerotic process are proatherogenic and prothrombotic oxidative events in the artery wall that may be inhibited by antioxidants.

The 1999 AHA Science Advisory2 recommended that the general population consume a balanced diet with emphasis on antioxidant-rich fruits, vegetables, and whole grains, advice that was consistent with the AHA Dietary Guidelines at the time. In the absence of data from randomized, controlled clinical trials, no recommendations were made with regard to the use of antioxidant supplements.

In the past 5 years, a number of controlled clinical studies have reported the effects of antioxidant vitamin and mineral supplements on CVD risk (see Tables 1 through 3).4–21 These studies have been the subject of several recent reviews22–26 and formed the database for the present article. In general, the studies presented in the tables differ with regard to subject populations studied, type and dose of antioxidant/cocktail administered, length of study, and study end points. Overall, the studies have been conducted on post–myocardial infarction subjects or subjects at high risk for CVD, although some studied healthy subjects.

In addition to dosage differences in vitamin E studies, some trials used the synthetic form, whereas others used the natural form of the vitamin. With regard to the other antioxidants, different doses were administered (eg, for ß-carotene and vitamin C). The antioxidant cocktail formulations used also varied. Moreover, subjects were followed up for at least 1 year and for as long as 12 years. In addition, a meta-analysis of 15 studies (7 studies of vitamin E, 50 to 800 IU; 8 studies of ß-carotene, 15 to 50 mg) with 1000 or more subjects per trial has been conducted to ascertain the effects of antioxidant vitamins on cardiovascular morbidity and mortality.27 Collectively, for the most part, clinical trials have failed to demonstrate a beneficial effect of antioxidant supplements on CVD morbidity and mortality. With regard to the meta-analysis, the lack of efficacy was demonstrated consistently for different doses of various antioxidants in diverse population groups.

Although the preponderance of clinical trial evidence has not shown beneficial effects of antioxidant supplements, evidence from some smaller studies documents a benefit of -tocopherol (Cambridge Heart AntiOxidant Study,13 Secondary Prevention with Antioxidants of Cardiovascular disease in End-stage renal disease study),15 -tocopherol and slow-release vitamin C (Antioxidant Supplementation in Atherosclerosis Prevention study),16 and vitamin C plus vitamin E (Intravascular Ultrasonography Study)17 on cardiovascular end points. To complicate matters, there is some evidence of potentially adverse effects of antioxidant supplements on CVD as assessed by angiographic end points. In the Women’s Angiographic Vitamin and Estrogen Study,21 postmenopausal women with coronary disease on hormone replacement therapy given vitamin E plus vitamin C had an unexpected significantly higher all-cause mortality rate and a trend for an increased cardiovascular mortality rate compared with the vitamin placebo women. Likewise, in the HDL-Atherosclerosis Treatment Study,20 subjects with angiographically demonstrated coronary artery disease on simvastatin/niacin and an antioxidant cocktail (vitamin E, ß-carotene, vitamin C, and selenium) had a 0.7% progression in stenosis after 3 years, compared with 0.4% regression in the group on only simvastatin/niacin. Thus, antioxidant supplements may have interfered with the efficacy of statin-plus-niacin therapy. Further evaluation showed that the addition of the antioxidant vitamins blunted the expected rise in the protective HDL-2 cholesterol and apolipoprotein A1 subfractions of HDL. In general, the studies showing either positive or adverse effects (especially for vitamins E, vitamins E and C, and the antioxidant cocktails) are much smaller studies than the larger clinical trials that consistently have not shown any beneficial effects of antioxidant supplements on several CVD end points.

Thus, in agreement with many in the field, we conclude that the existing scientific database does not justify routine use of antioxidant supplements for the prevention and treatment of CVD.25–28,29 This conclusion is consistent with the American College of Cardiology/American Heart Association 2002 Guideline Update for the management of patients with chronic stable angina, which states that there is no basis for recommending that patients take vitamin C or E supplements or other antioxidants for the express purpose of preventing or treating coronary artery disease (Class III, Level A Evidence).30 In addition, "Evidence-Based Guidelines for Cardiovascular Disease Prevention in Women"31 concludes that antioxidant vitamin supplements should not be used to prevent CVD, pending the results of ongoing trials (Class III, Level A Evidence). Whether or not to use vitamin E in highly specialized situations, such as in subjects on hemodialysis,15 also remains unsettled until further studies in this setting are conducted. Moreover, although there is some evidence of beneficial effects of antioxidant supplements, it also is apparent that some studies suggest adverse effects of antioxidant supplement use. An important question is: What should we be doing in clinical practice? At this time, there is little reason to advise that individuals take antioxidant supplements to reduce risk of CVD. Nonetheless, we recommend that antioxidant research continue in order to resolve whether the oxidative modification hypothesis is relevant to human atherosclerosis. It will be important to clarify the discrepancy between the randomized clinical trials and the population studies. The positive findings from observational studies with regard to vitamin E supplementation and lower rates of CVD may be a reflection of the generally healthy lifestyles and dietary intakes of supplement users. At this time, the scientific evidence supports recommending consumption of a diet high in food sources of antioxidants and other cardioprotective nutrients, such as fruits, vegetables, whole grains, and nuts, instead of antioxidant supplements to reduce risk of CVD.32,33 It does not support the use of antioxidant vitamin supplements.

The failure of these particular trials does not necessarily rule out a role for oxidative mechanisms in the pathogenesis of human atherosclerosis. Antioxidant compounds cannot be indiscriminately lumped together; they differ quantitatively and even qualitatively from one another. We still know too little about the oxidative mechanisms in vivo and lack biochemical markers with which to evaluate candidate antioxidant compounds. Moreover, antioxidant treatment may need to begin earlier in life to be effective. The discrepancy between the impressive observational data and the clinical trials could reflect the difference between lifelong exposure to an antioxidant-rich diet and a limited, 5-year exposure to antioxidant supplements. However, several other factors (such as identity, type, and form of antioxidant; particular antioxidant combinations; trial design issues; outcome measures; length; populations under study; etc) could also be important in explaining the lack of agreement between the predicted positive benefits and the results of the clinical trials conducted to date. Clearly, further research is needed.

THAT'S GREAT... NOW GO DO IT!

by Jerry Clark Jerry, I'm going to be the #1 person in my company...
Sounds Good, Now Go Do It!

Jerry, Just wait until the kids get back in school, I'm going to get busy then... Wonderful, Now Go Do It!

Jerry, once I get some new leads in, I'm going to rip this thing up... Superb, Now Go Do It!

Jerry, my wife said I can put more time in my Networking Business once my check gets to $500 per month... Terrific, Now Go Do It!

Jerry, I'll be walking across the stage winning an award at the next International convention... Cool, Now Go Do It!

Jerry, I'm going to go on a 30 Day Blitz and talk to at least 25 new people per day... Splendid, Now Go Do It!

Jerry, I'm going to make it big in Network Marketing and then go around the World changing people's lives like you do... Fantastic, Now Go Do It!

Jerry, I'm doing this business because I promised my Mother I would one buy her a new house one day... That's Nice, Now Go Do It!

Jerry, I'm sick and tired of working for someone else so I'm going to get serious about my Networking Business... Awesome, Now Go Do It!

Jerry, I'm going to Build an Empire so I can spend more time with my family... That's Beautiful, Now Go Do It!

Jerry, this is my year because I can just see my Bonus Check going through the Roof... Sounds Exciting, Now Go Do It!

Jerry, I'm going to get all of my people listening to your tapes and I know we will be more successful then... I like that thought, Now Go Do It!

Jerry, I know I told you I was going to do it for the last 5 years straight, but this year is different because I know I'm ready to go to the top... Yea, I remember, Now Go Do It!

Jerry, If you could fly out to my house and spend a month with me doing 3-Way calls and presentations, I know my business will explode... Well, not going to happen, Now Go Do It

Anyway! Jerry, If only... Ok, Now Go Do It!

Jerry, you don't understand... Sure, Now Go Do It !

Jerry, it would be nice if... Yea it would be, Now Go Do It!

Jerry, aren't you listening to... Probably not, Now Go Do It!

Folks... Understand this... Success doesn't reward you for what you're going to someday do... It rewards you for what you do... So stop contemplating, evaluating, hesitating, meditating, and deliberating... Pay attention to the words that are coming out of my mind... Jerry, I think I will read this Rhino Tip Again...

That's Great... Now Go Do It!